In recent years, cancer, especially primary liver cancer (including hepatocellular carcinoma and intrahepatic cholangiocarcinoma), has posed a serious threat to human health.In the field of liver cancer, exosomes play an important role in liver cancer initiation, metastasis and interaction with the tumor microenvironment.Exosomes are a class of nan
The p70 ribosomal S6 kinase (S6K) family is a group of highly conserved kinases in eukaryotes that regulates cell growth, cell proliferation, and stress response via modulating protein synthesis and ribosomal biogenesis.S6Ks are downstream effectors of the Target of Rapamycin (TOR) pathway, which connects nutrient and energy signaling to growth and
Background: Sparse data are available on rates MAGNESIUM CTRATE of drug-induced pruritus, a well-recognized adverse reaction.We sought to assess relative rates of pruritus associated with commonly prescribed medications.Methods: Using the electronic medical record system EPIC, retrospective data were collected on patients seen at Johns Hopkins who
The IslamicRevolutionof Irantookplaceinclaimofanindependentanti-arrogant discoursewithIslamicrootsintheworldarena.Howeveraftermorethanfortyyearsof thisrevolutionthemainconceptand discourse of the system remained unknown to many parts of the world.The importance of information and communicationinthepresentageontheonehand,andtheadventoftheInternetand
The activity of ghrelin, apelin and their receptors has been correlated to the control of some infectious diseases, besides the hypothesis of their role in the control of some Knife peripheral organs, among which ovaries.The aim of the present work was to highlight the presence and distribution of ghrelin, apelin and cognate receptors in the ovarie